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Imitrex®
(sumatriptan succinate tablets)
Drug Uses
Esgic Plus is a pain reliever and a
relaxant. Use this medicine to treat tension headaches.
How Taken
Take this medicine only as directed by
your doctor . Do not take more of it, do not take it more often, and do not take
it for a longer time than your doctor ordered. Adults should take one or 2
capsules or tablets every four hours as needed. If your medicine contains 325 or
500 milligrams (mg) of acetaminophen in each capsule or tablet, you should not
take more than six capsules or tablets a day.
Warnings/Precautions
If the medicine stops working as well as
it did when you first started using it, this may mean that you are in danger of
becoming dependent on the medicine. Do not try to get better pain relief by
increasing the dose. If you are having headaches more often than you did before
you started taking this medicine ;this is especially important if a new headache
occurs within 1 day after you took your last dose of this medicine, headaches
begin to occur every day, or a headache continues for several days in a row.
This may mean that you are dependent on the medicine. Continuing to take this
medicine will cause even more headaches later on . Your doctor can give you
advice on how to relieve the headaches.
Missed Dose
If your doctor has ordered you to take
this medicine according to a regular schedule and you miss a dose, take it as
soon as you remember. However, if it is almost time for your next dose, skip the
missed dose and go back to your regular dosing schedule. Do not double dose.
Possible Side Effects
Check with your doctor immediately if any
of the following side effects occur, especially if several of them occur
together: bleeding or crusting sores on lips; chest pain; fever with or without
chills; hive-like swellings (large) on eyelids, face, lips, and/or tongue;
muscle cramps or pain; red, thickened, or scaly skin; shortness of breath,
troubled breathing, tightness in chest, or wheezing; skin rash, itching, or
hives; sores, ulcers, or white spots in mouth (painful); sore throat; confusion
(mild); mental depression; unusual excitement (mild)
Storage
Keep out of the reach of children. Store
away from heat and direct light. Do not store this medicine in the bathroom,
near the kitchen sink, or in other damp places. Heat or moisture may cause the
medicine to break down.
Overdose
If you think you or anyone else may have
taken an overdose of this medicine, seek emergency medical attention. Taking an
overdose of this medicine or taking alcohol or CNS depressants with this
medicine may lead to unconsciousness or possibly death.
More Information
This medicine may cause drowsiness or
dizziness. Make sure you know how you react to this medicine before you drive,
use machines, or do anything else that could be dangerous if you are dizzy or
are not alert and clearheaded.
IMITREX Tablets contain sumatriptan (as the succinate), a selective
5-hydroxytryptamine1 receptor subtype agonist. Sumatriptan succinate is
chemically designated as
3-[2-(dimethylamino)ethyl]-N-methyl-indole-5-methanesulfonamide succinate (1:1).
The empirical formula is C14H21N3O2S•C4H6O4, representing a molecular weight of
413.5. Sumatriptan succinate is a white to off-white powder that is readily
soluble in water and in saline. Each IMITREX Tablet for oral administration
contains 35, 70, or 140 mg of sumatriptan succinate equivalent to 25, 50, or 100
mg of sumatriptan, respectively. Each tablet also contains the inactive
ingredients croscarmellose sodium, dibasic calcium phosphate, magnesium stearate,
microcrystalline cellulose, and sodium bicarbonate. Each 100-mg tablet also
contains hypromellose, iron oxide, titanium dioxide, and triacetin.
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