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Dovonex Ointment®

(calcipotriene ointment), 0.005%

Also see:  Dovonex Cream    Dovonex Scalp

FOR TOPICAL DERMATOLOGIC USE ONLY.
Not for Ophthalmic, Oral or Intravaginal Use.
 

Drug Uses
Dovonex Cream ?Ointment is indicated for the treatment of plaque psoriasis.

How Taken
Apply a thin layer of Dovonex Cream / Ointment to the affected skin twice daily and rub in gently and completely.

Warnings/Precautions
Use of Dovonex Cream / Ointment may cause transient irritation of both lesions and surrounding uninvolved skin. If irritation develops, you should discontinue using Dovonex Cream. Do not use this medication for any disorder other than that for which it was prescribed.

Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

Possible Side Effects
Some of the most frequent side effects that may occur while using Dovonex are: skin irritation, rash, pruritus, dermatitis and worsening of psoriasis.

Storage
Store at controlled room temperature 15°C - 25°C (59°F - 77°F). Do not freeze.

Overdose
Topically applied Dovonex can be absorbed in sufficient amounts to produce systemic effects. If an overdose is suspected, discontinue Donovex Cream and seek medical attention.

More Information
This medication is to be used only as directed by your physician. It is for external use only. Avoid contact with the face or eyes. As with any topical medication, you should wash your hands after application. Report to your physician any signs of adverse reactions.

DOVONEX (calcipotriene ointment) contains the compound calcipotriene, a synthetic vitamin D3, derivative for topical dermatological use.

Chemically, calcipotriene is

(5Z,7E, 22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19), 22-tetraene-1 alpha, 3 beta, 24-triol-,

with the empirical formula C27H40O3, a molecular weight of 412.6.

Calcipotriene is a white or off-white crystalline substance. DOVONEX Ointment contains calcipotriene 50 ug/g in an ointment base of dibasic sodium phosphate, edetate disodium, mineral oil, petrolatum, propylene glycol, tocopherol steareth-2 and water.