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Dovonex Cream®
(calcipotriene cream)
Cream, 0.005%
Also see: Dovonex
Scalp
Dovonex Ointment
FOR TOPICAL DERMATOLOGIC USE ONLY.
Not for Ophthalmic, Oral or
Intravaginal Use.
Drug Uses
Dovonex Cream ?Ointment is indicated for
the treatment of plaque psoriasis.
How Taken
Apply a thin layer of Dovonex Cream /
Ointment to the affected skin twice daily and rub in gently and completely.
Warnings/Precautions
Use of Dovonex Cream / Ointment may cause
transient irritation of both lesions and surrounding uninvolved skin. If
irritation develops, you should discontinue using Dovonex Cream. Do not use this
medication for any disorder other than that for which it was prescribed.
Missed Dose
If you miss a dose, use it as soon as you
remember. If it is near the time of the next dose, skip the missed dose and
resume your usual dosing schedule. Do not double the dose to catch up.
Possible Side Effects
Some of the most frequent side effects
that may occur while using Dovonex are: skin irritation, rash, pruritus,
dermatitis and worsening of psoriasis.
Storage
Store at controlled room temperature 15°C
- 25°C (59°F - 77°F). Do not freeze.
Overdose
Topically applied Dovonex can be absorbed
in sufficient amounts to produce systemic effects. If an overdose is suspected,
discontinue Donovex Cream and seek medical attention.
More Information
This medication is to be used only as
directed by your physician. It is for external use only. Avoid contact with the
face or eyes. As with any topical medication, you should wash your hands after
application. Report to your physician any signs of adverse reactions.
Dovonex® (calcipotriene cream) Cream, 0.005% contains calcipotriene monohydrate,
a synthetic vitamin D3 derivative, for topical dermatological use.
Chemically, calcipotriene monohydrate is
(5Z,7E,22E,24S)-24-cyclopropyl-9,10-secochola-5,7,10(19),
22-tetraene-1a,3b,24-triol monohydrate,
with the empirical formula C27H40O3†H2O, a
molecular weight of 430.6.
Calcipotriene monohydrate is a white or off-white crystalline substance. Dovonex
Cream contains calcipotriene monohydrate equivalent to 50 µg/g anhydrous
calcipotriene in a cream base of cetearyl alcohol, ceteth-20, diazolidinyl urea,
dichlorobenzyl alcohol, dibasic sodium phosphate, edetate disodium, glycerin,
mineral oil, petrolatum, and water.
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