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Colchicine®

Also
see: Naprosyn
Motrin
Zyloprim Allopurinol
Drug Uses
Colchicine is used to treat attacks of
gout.
How Taken
Take each dose of Colchicine with a full
glass of water. You may take this medicine up to once every hour until the pain
is relieved, until the maximum amount of medicine has been taken, or until
nausea, vomiting, or diarrhea occurs. To prevent an attack from occurring, you
may take Colchicine every day or several days a week. Do not take more doses
than your doctor prescribed.
Warnings/Precautions
Do not take Colchicine without first
talking to your doctor if you are breast-feeding a baby. Talk to your doctor if
you are or plan on becoming pregnant as this medicine may have harmful effects
on the unborn baby.
Missed Dose
If you miss a dose, use it as soon as you
remember. If it is near the time for the next dose, skip the missed dose and
resume your usual dosing schedule. Do not double the dose to catch up.
Possible Side Effects
Some of the side effects that may occur
while taking Colchicine include: difficulty breathing; closing of your throat;
swelling of your lips, tongue, or face; fever; rash; numbness or tingling.
Storage
Store Colchicine at room temperature away
from moisture and heat. Keep out of the reach of children.
Overdose
Symptoms of a colchicine overdose include
nausea; vomiting; stomach pain; diarrhea; muscle weakness; burning in your
throat, stomach, or skin; difficulty breathing; delirium; and seizures. An
overdose of colchicine can result in death. If you suspect an overdose, seek
immediate medical attention.
More Information
Tell your doctor and pharmacist about all
medicines that you are taking. Colchicine may interact with other drugs.
Colchicine is an alkaloid prepared from the dried corns and seeds of Colchicum
autumnale, the autumn crocus or meadow saffron. It is a pale yellow powder
soluble in water in 1:25 dilution.
Colchicine Tablets, USP are oral anti-inflammatory agents supplied in two dosage
strengths 0.5 mg (l/120 gr) and 0.6 mg (l/100 gr). The chemical name for
colchicine is
(S) N-(5,6,7,9-tetrahydro- 1,2,3, IO-tetramethoxy-9-oxobenzo
[alpha] heptaien-7-yl) acetamide.
Inactive Ingredients
0.5 mg tablet: Calcium carbonate, confectioner†s sugar (contains corn starch),
D& C Yellow No. 10, dextrin, stearic acid, sucrose and talc.
0.6 mg tablet: Acacia, corn starch, D& C Yellow No. 10, lactose, stearic acid
and talc.
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