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Claritin D®
(Loratadine)
Also see:
Allegra
Carisoprodol
Clarinex Cyclobenzaprine Flexeril Flextra
DS
Skelaxin Soma
Zanaflex
Clarinex-D Claritin
Crixivan
Drug Uses
Claritin-D is used to relieve hay fever
and allergy symptoms, including sneezing, runny nose, and red, itchy, tearing
eyes. Claritin-D is in a class of medications called antihistamines. It works by
blocking histamine, a substance in the body that causes allergic symptoms.
Claritin-D may cause less drowsiness than other antihistamines.
How Taken
Claritin-D comes as a tablet to take by
mouth. 12 Hour Tablet: One tablet twice a day (every 12 hours); 24 Hour Tablet:
One tablet daily taken with a full glass of water. You should not to break or
chew the tablet and you should take the 24 hour tablet with a full glass of
water.
Warnings/Precautions
Before taking Claritin-D, tell your doctor
if you have asthma or another lung disease; diabetes; thyroid problems; glaucoma
or increased pressure in the eye; urinary retention or an enlarged prostate;
narrowing of the esophagus or gastrointestinal tract or difficulty swallowing;
kidney or liver disease; or heart disease, high blood pressure, or an irregular
heartbeat. You may not be able to take Claritin-D, or you may require a dosage
adjustment or special monitoring during treatment if you have any of the
conditions listed above. Claritin-D is in the FDA pregnancy category B. This
means that it is not expected to be harmful to an unborn baby. Do not take
Claritin-D without first talking to your doctor if you are pregnant. Claritin-D
passes into breast milk and may affect a nursing baby. Do not take Claritin-D
without first talking to your doctor if you are breast-feeding a baby.
Claritin-D has not been approved for use by children younger than 12 years of
age.
Missed Dose
Take the missed dose as soon as you
remember it. However, if it is almost time for the next dose, skip the missed
dose and continue your regular dosing schedule. Do not take a double dose to
make up for a missed one.
Possible Side Effects
Serious side effects are not likely to
occur with the use of Claritin-D. If you experience any of the following serious
side effects, stop taking Claritin-D and contact your doctor immediately or seek
emergency medical attention: an allergic reaction (difficulty breathing; closing
of your throat; swelling of your lips, tongue, or face; or hives); an irregular
heartbeat; or seizures. Other, less serious side effects may be more likely to
occur. Continue to take Claritin-D and talk to your doctor if you experience
dizziness; headache; insomnia; nervousness; nausea, diarrhea, or abdominal
discomfort; dry mouth; dry skin or itchiness; or discoloration of urine. Side
effects other than those listed here may also occur. Talk to your doctor about
any side effect that seems unusual or that is especially bothersome.
Storage
Protect Claritin-D from light and store in
a dry place. Store between 15-25°C (59-77°F).
Overdose
Seek emergency medical attention. Symptoms
of a Claritin-D overdose include headache, drowsiness, an irregular heartbeat,
nausea and vomiting, sweating, increased thirst, weakness, and restlessness.
More Information
Use caution when driving, operating
machinery, or performing other hazardous activities. Claritin-D may cause
dizziness. If you experience dizziness, avoid these
Claritin-D 12 Hour Extended Release Tablets: Claritin-D 12 hour extended release
tablets contain 5 mg loratadine in the tablet coating for immediate release and
120 mg pseudoephedrine sulfate equally distributed between the tablet coating
for immediate release and the barrier-coated extended release core.
The inactive ingredients are acacia, butylparaben, calcium sulfate, carnauba
wax, corn starch, lactose, magnesium stearate, microcrystalline cellulose,
neutral soap, oleic acid, povidone, rosin, sugar, talc, titanium dioxide, white
wax, and zein.
Claritin-D 24 Hour Extended Release Tablets: Claritin-D 24 hour extended release
tablets contain 10 mg loratadine in the tablet film coating for immediate
release and 240 mg pseudoephedrine sulfate in the tablet core which is released
slowly allowing for once-daily administration.
The inactive ingredients for oval, biconvex Claritin-D 24 hour extended release
tablets are calcium phosphate, carnauba wax, ethylcellulose, hydroxypropyl
methylcellulose, magnesium stearate, polyethylene glycol, povidone, silicon
dioxide, sugar, titanium dioxide, and white wax.
Loratadine is a long-acting antihistamine having the empirical formula
C22H23ClN2O2; the chemical name
ethyl
4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate.
The molecular weight of loratadine is 382.89. It is a white to off-white powder,
not soluble in water, but very soluble in acetone, alcohol, and chloroform.
Pseudoephedrine sulfate is the synthetic salt of one of the naturally occurring
dextrorotatory diastereomers of ephedrine and is classified as an indirect
sympathomimetic amine. The empirical formula for pseudoephedrine sulfate is
(C10H15NO)2H2SO4; the chemical name is a-[1-(methyl-amino) ethyl]-[S-(R*,R*)]-benzenemethanol
sulfate (2:1)(salt).
The molecular weight of pseudoephedrine sulfate is 428.54. It is a white powder,
freely soluble in water and methanol and sparingly soluble in chloroform.
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