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Biaxin®
Filmtab®
(clarithromycin tablets, USP)
Biaxin® XL
Filmtab®
(clarithromycin extended-release tablets)
Biaxin®
Granules
(clarithromycin for oral suspension, USP)
Also see: Amoxicillin
Prevacid
Amikacin
Amikin Amoxil Augmentin
Augmentin ES
Augmentin XR Prevpac
Trimox
To reduce the development of drug-resistant bacteria and maintain the
effectiveness of Biaxin and other antibacterial drugs, Biaxin should be used
only to treat or prevent infections that are proven or strongly suspected to be
caused by bacteria.
Clarithromycin is a semi-synthetic macrolide antibiotic. Chemically, it is
6-0-methylerythromycin. The molecular formula is C38H69NO13, and the molecular
weight is 747.96.
Clarithromycin is a white to off-white crystalline powder. It is soluble in
acetone, slightly soluble in methanol, ethanol, and acetonitrile, and
practically insoluble in water.
Biaxin is available as immediate-release tablets, extended-release tablets, and
granules for oral suspension.
Each yellow oval film-coated immediate-release Biaxin tablet (clarithromycin
tablets, USP) contains 250 mg or 500 mg of clarithromycin and the following
inactive ingredients:
250 mg tablets: hypromellose, hydroxypropyl cellulose, croscarmellose sodium,
D&C Yellow No. 10, FD&C Blue No. 1, magnesium stearate, microcrystalline
cellulose, povidone, pregelatinized starch, propylene glycol, silicon dioxide,
sorbic acid, sorbitan monooleate, stearic acid, talc, titanium dioxide, and
vanillin.
500 mg tablets: hypromellose, hydroxypropyl cellulose, colloidal silicon
dioxide, croscarmellose sodium, D&C Yellow No. 10, magnesium stearate,
microcrystalline cellulose, povidone, propylene glycol, sorbic acid, sorbitan
monooleate, titanium dioxide, and vanillin.
Each yellow oval film-coated Biaxin XL tablet (clarithromycin extended-release
tablets) contains 500 mg of clarithromycin and the following inactive
ingredients: cellulosic polymers, D&C Yellow No. 10, lactose monohydrate,
magnesium stearate, propylene glycol, sorbic acid, sorbitan monooleate, talc,
titanium dioxide, and vanillin.
After constitution, each 5 mL of Biaxin suspension (clarithromycin for oral
suspension, USP) contains 125 mg or 250 mg of clarithromycin. Each bottle of
Biaxin granules contains 1250 mg (50 mL size), 2500 mg (50 and 100 mL sizes) or
5000 mg (100 mL size) of clarithromycin and the following inactive ingredients:
carbomer, castor oil, citric acid, hypromellose phthalate, maltodextrin,
potassium sorbate, povidone, silicon dioxide, sucrose, xanthan gum, titanium
dioxide and fruit punch flavor.
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